Fig. 2.

Mean change scores from baseline at each follow-up visit in treatment and placebo groups. Vertical bars represent standard deviation. Blue arrow indicates direction of improvement. (A) Positive change scores in ADAS-cog indicate worsening impairment from baseline. (B) Positive change scores in ADCS-ADL indicate improvement from baseline. (C) Positive change scores in MMSE indicate improvement from baseline. (D) Positive change scores in NPI indicate worsening impairment from baseline. Abbreviations: ADAS-cog, Alzheimer's Disease Assessment Scale–cognitive subscale; MMSE, Mini–Mental State Examination; ADCS-ADL, Alzheimer's Disease Cooperative Study–Activities of Daily Living Scale; NPI, Neuropsychiatric Inventory.