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IC50 values for inhibition of human and rat α6/α3β2β3 nAChRs by PeIA, PnIA, and TxIB
Values in parentheses indicate the 95% CI of the data obtained from four oocytes per IC50 determination.
| α-Ctx | IC50 |
|
|---|---|---|
| Human | Rat | |
| nm | ||
| PeIA | 16.0 (14.2–18.1) | 16.3 (13.2–20.2) |
| PnIA | 2.8 (2.0–3.8) | 3.3 (3.0–3.6) |
| TxIB | 291 (255–332) | 207 (175–244) |
