Table 1. Experimental conditions and macromolecular properties of Gem-based P(OEGMA-co-MPDL) and P(MMA-co-MPDL) polymer prodrugs.

Prodrug	Alkoxyamine	Methacrylic ester	f MPDL,0	Conv. a (%)/temps (h)	M n b (g mol–1)	Total DPn	Đ b	F MPDL c
P1	Gem-AMA-SG1	OEGMA	0.2	40/8	15 500	51	1.54	0.06
P2	Gem-AMA-SG1	OEGMA	0.4	28/8	10 200	34	1.39	0.12
P3	Gem-AMA-SG1	OEGMA	0.7	18/8	10 000	35	1.37	0.25
P1d	Gem-digly-AMA-SG1	OEGMA	0.2	61/8	11 500	36	1.24	0.07
P2d	Gem-digly-AMA-SG1	OEGMA	0.4	36/8	13 200	43	1.24	0.11
P3d	Gem-digly-AMA-SG1	OEGMA	0.7	22/8	11 200	38	1.13	0.22
P4	Gem-AMA-SG1	MMA	0.2	35/5	13 200	119	1.27	0.10
P5	Gem-AMA-SG1	MMA	0.4	34/5	9900	83	1.28	0.19
P6	Gem-AMA-SG1	MMA	0.7	23/5	10 300	82	1.21	0.29
P4d	Gem-digly-AMA-SG1	MMA	0.2	56/8	15 400	138	1.34	0.07
P5d	Gem-digly-AMA-SG1	MMA	0.4	55/8	12 400	106	1.29	0.12
P6d	Gem-digly-AMA-SG1	MMA	0.7	33/8	10 900	84	1.20	0.29

^aMethacrylic ester conversion determined by ¹H NMR.

^bDetermined by SEC after precipitation.

^cDetermined by ¹H NMR.