Table 2. Characterization of Gem-P(MMA-co-MPDL) and Gem-digly-P(MMA-co-MPDL) nanoparticles.
Prodrug | D z a (nm) | PSD a | ζ b (mV) | % Gem c (wt%) |
P4 | 196 | 0.09 | –55 | 2.0 |
P5 | 162 | 0.10 | –57 | 2.6 |
P6 | 174 | 0.09 | –55 | 2.5 |
P4d | 109 | 0.13 | –37 | 1.7 |
P5d | 110 | 0.11 | –38 | 2.1 |
P6d | 117 | 0.10 | –46 | 2.4 |
aDetermined by DLS.
bZeta potential, determined using the DLS apparatus.
cDetermined according to: % Gem = Mw,Gem/Mn,SEC.