Table 1. Descriptive statistics of the ICU patient population over the first days after admission.
| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | |
|---|---|---|---|---|---|
| days remaining of admission | 5.46 (8.60) | 5.81 (9.41) | 6.76 (10.54) | 7.74 (11.58) | 8.69 (12.49) |
| sex (male) | 0.59 | - | - | - | - |
| APACHE-II score | 15.35 (6.39) | - | - | - | - |
| age /years | 61.37 (17.27) | - | - | - | - |
| ventilated (yes) | 0.40 | 0.29 | 0.32 | 0.35 | 0.38 |
| min HR /bpm | 71.2 (16.14) | 74.37 (15.5) | 75.44 (15.58) | 75.5 (16) | 75.55 (15.96) |
| max HR /bpm | 101.62 (21.36) | 100.45 (20.81) | 101.84 (21) | 101.96 (20.75) | 101.84 (20.58) |
| min MAP /mmHg | 64.82 (12.51) | 68.25 (13.13) | 69.29 (13.78) | 69.87 (14.14) | 70.14 (15.09) |
| max MAP /mmHg | 102.41 (19.61) | 100.66 (19.65) | 102.55 (20.26) | 104.07 (20.7) | 104.52 (21.05) |
| min / /kPa | 33.77 (14.99) | 33 (13.79) | 31.3 (13.33) | 30.73 (13.05) | 30.37 (12.84) |
| max / /kPa | 48.24 (18.98) | 43.62 (15.6) | 41.83 (15.28) | 41.27 (15.07) | 40.9 (14.99) |
| min Lactate /mmol/l | 1.31 (1.35) | 1.22 (1.21) | 1.18 (1.12) | 1.16 (1.05) | 1.16 (0.98) |
| max Lactate /mmol/l | 2.80 (2.65) | 2.18 (2.01) | 2.00 (1.78) | 1.93 (1.71) | 1.91 (1.56) |
| min Sodium /mmol/l | 136.56 (5.03) | 137.15 (5.09) | 137.69 (5.37) | 138.33 (5.49) | 138.85 (5.64) |
| max Sodium /mmol/l | 140.49 (4.93) | 140.13 (5.24) | 140.52 (5.55) | 141.13 (5.78) | 141.65 (5.94) |
| min Potassium /mmol/l | 3.93 (0.58) | 4.01 (0.48) | 4.01 (0.47) | 4.02 (0.45) | 4.05 (0.46) |
| max Potassium /mmol/l | 4.85 (0.74) | 4.66 (0.57) | 4.63 (0.54) | 4.64 (0.54) | 4.67 (0.54) |
| min PH /pH | 7.32 (0.09) | 7.36 (0.07) | 7.37 (0.07) | 7.38 (0.07) | 7.38 (0.07) |
| max PH /pH | 7.42 (0.06) | 7.43 (0.06) | 7.43 (0.06) | 7.44 (0.05) | 7.44 (0.06) |
| min Creatinine /μmol/l | 118.51 (109.32) | 117.38 (96.47) | 111.72 (88.75) | 108.13 (82.51) | 107.16 (80.39) |
| max Creatinine /μmol/l | 136.05 (136.13) | 121.51 (102.74) | 114.55 (92.93) | 110.5 (85.73) | 109.53 (84.09) |
| min CRP /mg/l | 77.34 (91.38) | 118.91 (91.8) | 126.79 (94.95) | 116.95 (91.73) | 106.19 (88.03) |
| max CRP /mg/l | 115.21 (104.85) | 155.1 (110.32) | 157.29 (109.24) | 144.74 (104.9) | 131.32 (100.82) |
| noradrenaline /μg/kg/24h | 84.0 (168.0) | 81.6 (177.7) | 81.8 (161.8) | 77.8 (148.1) | 79.2 (145.8) |
| adrenaline /μg/kg/24h | 64.8 (126.0) | 135.0 (288.4) | 108.1 (230.9) | 120.1 (131.4) | 102.9 (109.3) |
| vasopressin /units/24h | 777.0 (1327.5) | 778.8 (1767.0) | 818.4 (2102.4) | 900.0 (1560.0) | 540.0 (1899.6) |
Figures represent arithmetic mean (standard deviation) for numerical variables and proportions for all binomial variables, with the exception of the drugs for which median (inter-quartile range) is shown. All values are calculated from all non-missing data, after removal of outliers, and before imputation of missing data.