Table 1.
IC50 determination of P1 and P2 in leukemia/lymphoma and non-cancerous cell lines
| Cell line | Cell type | Disease | Pl IC50aμM) | SIb | P2 IC50 (μM) | SI | Age | Ethnicity | Sex |
|---|---|---|---|---|---|---|---|---|---|
| BJAB | B Lymphocyte | Burkitt’s Lymphoma | 0.29 ± 0.02 | 25.86 | 2.50 ± 0.06 | 4.52 | 5 | African | F |
| CEM | T Lymphoblast | Acute Lymphoblastic Leukemia | 0.33 ± 0.01 | 22.73 | 3.41 ± 1.24 | 3.32 | 4 | Caucasian | F |
| HL-60 | Promyoblast | Acute Myelocytic Leukemia | 0.52 ± 0.06 | 14.42 | 1.94 ± 0.09 | 5.83 | 36 | Caucasian | F |
| Jurkat | T Lymphocyte | Acute Lymphocytic Leukemia | 0.27 ± 0.03 | 27.78 | 1.24 ± 0.12 | 9.12 | 14 | - | M |
| Nalm-6 | pre-B cell | Acute Lymphoblastic Leukemia | 0.36 ± 0.02 | 20.83 | 0.86 ± 0.04 | 13.15 | 19 | - | M |
| Ramos | B Lymphocyte | Burkitt’s Lymphoma | 0.23 ± 0.01 | 32.6 | 0.67 ± 0.01 | 16.88 | 3 | Caucasian | M |
| Hs27 | Fibroblast | None | 6.24 ± 0.99 | - | 11.38 ± 0.54 | - | NBC | Black | M |
| MCF-10A | Epithelial | Fibrocystic Disease | 8.76 ± 1.14 | - | 11.24 ± 0.80 | - | 36 | Caucasian | F |