Table 1. T6P Specifically Binds KIN10.
Ligand (50 µM) | Target | |
---|---|---|
KIN10 | KIN10 (K48A) | |
ATP | + | – |
T6P | + | + |
Sucrose | – | n.d. |
Trehalose | – | n.d. |
Sorbitol | – | n.d. |
Suc-6′-P | – | n.d. |
MST was performed to evaluate the interactions between target proteins [KIN10 and KIN10 (K48A)] and potential ligands. +, Interaction detected; −, lack of interaction; n.d., not determined.