Table 2.

Univariate and Multivariate Analysis of Variables Associated with OS in Patients with HCC

	Univariate analysis			Multivariate analysis
Variables	p	HR	95% CI	p	HR	95% CI
DNER expression (high/low)	0.005*	2.701	1.352–5.398	0.011*	2.582	1.239–5.380
Age (<60/≥60)	0.456	1.264	0.683–2.340
Gender (female/male)	0.030*	0.509	0.276–0.937	0.023*	0.480	0.254–0.906
Grade (G1+G2/G3+G4)	0.841	1.065	0.577–1.964
Pathologic stage (I + II/III+IV)	0.021*	2.054	1.113–3.789	0.701	0.739	0.157–3.472
Pathologic-T (T1+T2/T3+T4)	0.031*	1.981	1.066–3.680	0.296	2.266	0.489–10.506
Pathologic-M (M0/M1)	0.298	1.739	0.613–4.937
Pathologic-N (N0/N1)	0.076	2.996	0.891–10.067

^*p < 0.05.

HR, hazard ratio; OS, overall survival.