Table 4.

The genes of cytochrome P450 family were significantly downregulated, suggesting that the YDCS model can reduce lipid metabolism and biotransformation function in rats. On the contrary, RAWA can increase lipid metabolism and biotransformation function.

The serial number	Gene name	Fold change	P-val	GOid	GO function
ENSRNOG00000055078	Cyp4b1	0.42533	0.03924	GO:0055114	Energy metabolism
ENSRNOG00000019500	Cyp1a1	0.253766	0.0269	GO:0032496	Lipid metabolism
ENSRNOG00000002134	Cyp4a2	2.497622	0.00689	GO:0003924	Amino acid metabolism
ENSRNOG00000032261	Cyp2d4	0.463307	0.00951	GO:0019369	Lipid metabolism
ENSRNOG00000003510	Fmo2	0.285916	0.02557	GO:0006739	NADP metabolism
ENSRNOG00000029478	Cyp4f39	2.243402	0.0016	GO:0016705	Energy metabolism
ENSRNOG00000042714	RGD1559459	2.439187	0.03076	GO:0052696	NADP metabolism