Table 1.

Topics assessed and implications for system design

High-level topic	Sub-topic	How insights will guide design
Current medication-taking process	Perceived medication adherence	Which individuals should be targeted; USE-MI adoption may be higher among poor adherers
	Current medication storage method	What storage methods USE-MI may need to accommodate
	Schedule of medication-taking	Timing and frequency of gesture-recognition and reminders (affects algorithm design and battery life)
	Types of medication dose reminders	Whether USE-MI will support or interfere with current reminder approaches
	Whether medications are taken with liquid or food	Whether the gesture detection algorithms should include liquid or food intake
Physical act of taking medications	Hand(s) used to complete medication-taking actions	Types of gestures needing to be recognized, preferred wrist for wearing device
Feedback regarding the USE-MI system	Preferences for two different wrist-worn devices	Choice of wrist-worn device (Microsoft Band, Sony Android Wear Watch)
	Preferences for reminder method	Choice of reminder method(s) (phone call, email, text, app, on wrist-worn device)
	Preferences for summative medication-taking feedback method	Choice of summative feedback method (email, portal, app) and recipient (self, physician)
	Willingness to adopt the USE-MI system	Tailor USE-MI to persons struggling with adherence to HIV-related medications