Table 1. Baseline information by randomisation group and non-randomised comparison group.
| Number (%) | ||||
|---|---|---|---|---|
| Characteristic | Category | High-intensity PZQ
(n=113) |
Low-intensity PZQ
(n=113) |
Comparison
(n=137) |
| Sex | Male | 87(77.0) | 90(79.7) | 72(52.6) |
| Female | 26(23.0) | 23(20.3) | 65(47.4) | |
| Age (years) | Median (IQR) | 29 (24-33) | 30 (26-36) | 30 (26-36) |
| Age group | 18–24 | 29(25.7) | 21(18.6) | 25(18.3) |
| 25–34 | 64(56.6) | 55(48.7) | 62(45.2) | |
| 35–59 | 20(17.7) | 37(32.7) | 50(36.5) | |
| Education | None | 11(9.7) | 10(8.9) | 12(8.8) |
| Primary | 88(77.9) | 86(76.1) | 102(75.4) | |
| Secondary | 14(12.4) | 17(15.0) | 23(16.8) | |
| Marital | Single, never married | 11(9.7) | 20(17.7) | 14(10.2) |
| Married | 62(54.9) | 60(53.1) | 82(59.8) | |
| Single, ever married | 40(35.4) | 33(29.2) | 41(30.0) | |
| Occupation | Fishing/related | 88(77.9) | 83(73.4) | 83(73.4) |
| Small scale business | 9(8.0) | 8(7.1) | 8(7.1) | |
| Bar/restaurant | 4(3.5) | 7(6.2) | 7(6.2) | |
| Other | 12 (10.6) | 15(13.3) | 15(13.3) | |
| CD4 count | Mean ln (SD) | 6.5(0.33) | 6.4(0.31) | 6.4(0.36) |
| †Viral Load | Mean log 10 (SD) | 4.5(1.01) | 4.5(0.74) | 4.4(0.98) |
| Schistosoma (Kato
Katz microscopy) |
Prevalence | 113(100) | 113(100) | 0(0.0) |
|
*Geometric mean
egg count (95%CI) |
244.2(192.3-310.1) | 228.0(181.6-286.3) | N/A | |
| Schistosoma (serum
circulating anodic antigen (CAA)) |
Prevalence | 99(87.6) | 101(89.4) | 47(34.3) |
|
*Geometric mean
concentration pg/ml (95%CI) |
1708.2(1178.6-
2475.6) |
1877.8(1277.3-
2760.7) |
482.2(293.3-
792.7) |
|
| Other worms | Prevalence | 11(9.7) | 21(18.6) | 22(16.1) |
PZQ praziquantel. †12 volunteers (9-Low-intensity PZQ arm and 3-comparison) had undetectable viral loads at baseline. * Geometric mean among those infected. Figures in brackets are percentages unless otherwise indicated in column 2, IQR-Interquartile range.