Table 2. Adjusted ratio of geometric means for the primary outcome (viral load) and CD4 counts at 12 and 60 weeks by randomisation and comparison group.
| Outcome | Randomisation Group | 12 weeks | 60 weeks | ||||
|---|---|---|---|---|---|---|---|
| Mean (SD) $ | aGMR * | P-value | Mean (SD) $ | aGMR * | P-value | ||
| Viral load | Low-intensity PZQ | 4.2 (1.16) | 1.00 | 3.6 (1.57) | 1.00 | ||
| High-intensity PZQ | 4.3 (1.08) | 0.90 (0.65-1.25) | 0.55 | 4.0 (1.22) | 1.88 (0.78-4.53) | 0.16 | |
| Comparison | 4.1 (1.22) | 1.18 (0.83-1.69) | 0.36 | 3.6 (1.47) | 0.92 (0.39-2.18) | 0.84 | |
| CD4 count | Low-intensity PZQ | 6.3 (0.38) | 1.00 | 6.3 (0.40) | 1.00 | ||
| High-intensity PZQ | 6.4 (0.38) | 0.99 (0.93-1.07) | 0.96 | 6.3 (0.40) | 0.94 (0.86-1.02) | 0.15 | |
| Comparison | 6.3 (0.41) | 0.99 (0.93-1.07) | 0.97 | 6.2 (0.42) | 1.00(0.91-1.09 | 0.98 | |
PZQ praziquantel. *aGMR - adjusted ratio of geometric means, $ mean –Viral load transformed on log10 and CD4 on natural logarithm, adjusted for age and baseline viral load or CD4 count; “Low-intensity PZQ” was the reference group