Figure 3.

aJIA-ACR responses, CID_ACR/CID_JADAS rates and clinical remission on medication rates as per CR_ACR or CR_JADAS over time (observed data). n denotes the number of patients available at that time point; denominator was equal to 177 patients as per the ITT principle in the pivotal study. Clinical remission on medication, defined as CID (ACR or JADAS) for 6 continuous months. aJIA-ACR, adapted juvenile idiopathic arthritis by American (online supplementary appendix) College of Rheumatology criteria; BSL, baseline; CID_ACR, clinically inactive disease by ACR criteria; CID_JADAS, clinically inactive disease by Juvenile Arthritis Disease Activity Score criteria; CR, clinical remission; CR_ACR, CR by American College of Rheumatology criteria; CR_JADAS, CR by Juvenile Arthritis Disease Activity Score criteria; ITT, intent-to-treat.