Table 5.
Unpublished data from https://clinicaltrials.gov website
| Comparison (ClinicalTrial.gov identifier) |
Year | Duration (months) |
Number of patients | Study type | Results |
| Travoprost (sofZia) vs Latanoprost BAK (NCT00798759) |
2008 | 3 | 215 | Double masked RCT | OSDI score slightly better with SofZia TBUT the same |
| Travoprost (sofZia) vs Latanoprost BAK (NCT00690794) |
2008 | 3 | 726 | Double masked RCT | OSDI change similar Absence of corneal staining similar (37 sofZia, 40 BAK) |
| Travoprost (sofZia) vs Latanoprost BAK (NCT00527592) |
2007 | Not stated | 54 (comparison made between eyes) | Double masked RCT | Comfort after dose equal |
BAK, benzalkonium chloride; OSDI, Ocular SurfaceDisease Index; RCT, randomised controlled trials; TBUT, tear breakup time.