Table 6.

Genotype frequencies of TLR2 gene polymorphism in colorectal cancer tumor located in

SNP ID	Genotype	Colon, n (frequency)	Controls, n (frequency)	OR	95% CI	χ2 value	P-value*
Colon area vs control
rs3804099	CC	14 (0.21)	27 (0.26)	Ref
	CT	27 (0.42)	47 (0.47)	1.11	0.50–2.47	0.06	0.80
	TT	24 (0.37)	28 (0.27)	1.65	0.71–3.85	1.37	0.24
	CT + TT	51 (0.79) (0.)	75 (0.74)	1.31	0.63–2.74	0.52	0.47
	C	55 (0.42)	101 (0.49)	Ref
	T	75 (0.58)	103 (0.51)	1.34	0.86–2.08	1.65	0.20
rs3804100	CC	2 (0.03)	2 (0.02)	Ref
	CT	7 (0.10)	19 (0.18)	0.37	0.04–3.14	0.88	0.35
	TT	60 (0.87)	82 (0.80)	0.73	0.10–5.34	0.10	0.76
	CT + TT	67 (0.97)	101 (0.98)	0.66	0.09–4.83	0.17	0.68
	C	11 (0.08)	23 (0.11)	Ref
	T	127 (0.92)	183 (0.89)	1.45	0.68–3.08	0.95	0.33
rs4696480	AA	15 (0.25)	25 (0.27)	Ref
	AT	25 (0.42)	41 (0.45)	1.02	0.45–2.27	0.00	0.97
	TT	20 (0.33)	26 (0.28)	1.28	0.54–3.05	0.32	0.57
	AT + TT	45 (0.75)	67 (0.73)	1.12	0.53–2.35	0.09	0.77
	A	55 (0.46)	91 (0.49)	Ref
	T	65 (0.54)	93 (0.51)	1.16	0.73–1.83	0.38	0.54
Rectum area vs control
rs3804099	CC	4 (0.12)	27 (0.26)	Ref
	CT	18 (0.53)	47 (0.47)	2.59	0.79–8.43	2.60	0.11
	TT	12 (0.35)	28 (0.27)	2.89	0.83–10.09	2.92	0.09
	CT + TT	30 (0.82)	75 (0.74)	2.70	0.87–8.38	3.13	0.077
	C	26 (0.38)	101 (0.49)	Ref
	T	42 (0.62)	103 (0.51)	1.58	0.90–2.78	2.60	0.11
rs3804100	CC	0 (0.0)	2 (0.02)	Ref
	CT	5 (0.15)	19 (0.18)	1.41	0.06–33.93	0.52	0.47
	TT	28 (0.85)	82 (0.80)	1.73	0.08–37.06	0.68	0.41
	CT + TT	33 (1)	101 (0.98)	1.65	0.08–35.24	0.65	0.42
	C	5 (0.08)	23 (0.11)	Ref
	T	61 (0.92)	183 (0.89)	1.53	0.56–4.20	0.70	0.40
rs4696480	AA	8 (0.23)	25 (0.27)	Ref
	AT	19 (0.56)	41 (0.45)	1.45	0.55–3.80	0.57	0.45
	TT	7 (0.21)	26 (0.28)	0.84	0.27–2.67	0.09	0.77
	AT + TT	26 (0.77)	67 (0.73)	1.21	0.49–3.0	0.17	0.68
	A	35 (0.51)	91 (0.49)	Ref
	T	33 (0.49)	93 (0.51)	0.92	0.53–1.6	0.08	0.78

Note:

^*P<0.05.

Abbreviations: Ref, reference; SNP, single-nucleotide polymorphism.