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. 2018 Nov 14;13:3733–3747. doi: 10.2147/COPD.S183100

Table S4.

Transcript factors of common key genes screened by indirect PPi

TP53 IL-8 PIK3CA ELANE CCR2 CXCR2

AHR MEIS1 ALX3 MYB AP2GAMMA SPIB ALX3 TEF1 AHRHIF PMX1
AML1 MTF1 AP1 NF1C BCL6 PARP AML1 THAP1 AML1 POU4F3
AP1 MYB BCL6 NFE2 CBF NR2C2 AP1 TORC2 AP2REP PRRX2
AP2GAMMA MYOGENIN CDX1 NKX61 CDX AP2GAMMA USF BARHL1 RORA1
BEN MZF1 CDX2 NMYC CDX2 BRCA USF2 BARHL2 RPC155
BRCA NEUROD CDXA NURR1 CDXA HSPA1L CEBP ZBTB2 BEN RXRA
CACD NFAT1 CETS1 PARP CHCH KID3 CEBPB ZEB1 BRCA SATB1
CDX1 NFAT3 CFOS PEA3 CPBP EGR1 CEBPD ZNF333 BRN1 SMAD2
CDX2 NFAT4 CMYB PLZFB EGR3 GABPA CMYB CDX1 SOX10
CEBP NKX25 CPBP PMX1 ETF CPBP CEBPA SOX17
CEBPA NKX2B CREB PRRX2 ETS1 CPEB1 CEBPB SOX18
CETS1 NMYC ELF1 RAX FOS HSPA1A DLX3 CHCH SOX4
CHCH NR1B2 ELK1 RORBETA FOSL1 CHCH E2A CP2 SOX5
CJUN OSX EMX1 SATB1 FOXM1 CPBP E2F1 CPBP SPI1
CMAF PARP ETS2 SF1 FOXO1A E2F3 EGR3 DMBX1 SPIB
CMYB PAX4 ETV7 SOX17 GABPA EGR1 EMX1 E2A SREBP2
CPBP PEA3 EVX1 SOX4 GATA3 KLF7 EVX1 E2F1 SRY
CPEB1 PITX2 EVX2 SPI1 GKLF KLF8 EVX2 E2F3 STAT3
DR4 PLAGL2 FLI1 SPIB HFH8 LKLF FOXK1 ELF1 TAL1
E2F3 PRRX2 FOSL2 SREBP1 HNF3A MOVOB FOXP3 ETS TCF1
EBF1 PU1 FOXC1 TAF1 HOXA13 PLAGL2 GATA1 ETV7 TCF11
EGR1 PUR1 FOXD2 TATA ISL2 SP2 GKLF FOXC1 TCFE2A
EHF RELA FOXD3 TBP KID3 SP3 GR FOXO1A TFAP2C
ELF1 RORBETA FOXG1 TEF1 KLF SP6 HMGIY GATA2 TORC2
ELF5 SALL2 FOXI1 TTF1 LKLF VMYB HOXA10 GKLF USF2
ELK1 SATB1 FOXK1 ZNF333 MAZR ZBTB2 HOXA13 GMEB2 VDRRXRALPHA
ETS2 SMAD FOXL1 MITF HOXA2 GR ZBTB2
ETV7 SMAD2 FOXM1 NFAT1 HOXD3 HOXA13 ZFP770
FLI1 SMAD5 FOX01 NFAT4 HSF2 HSF4 ZNF333
FOXA1 SOX10 FOXO1A NFE4 IK IK ZNF536
FOXJ3 SOX11 FOXO3 NR2E1 IK2 ING4
FOXL1 SOX17 FOXO4 PLZFB KID3 IPF1
FOXM1 SOX18 FOXO6 PMX1 KLF IRF7
FOXO1 SOX30 FOXP3 RXRA LHX2 ISL2
FOXO1A SOX4 FRA1 SALL2 LKLF IKD3
FOXO3A SOX9 FXR SATB1 MAX LBP1
FOXP3 SPI1 GATA1 SMAD5 MEOX2 LMX1
FRA1 SPIB GATA3 SOX4 MYB LPOLYA
GABPA SREBP1 GATA4 SOX5 MYCMAX MEF2C
GATA1 SRY GATA5 SPIB NF1A MOVOB
GATA2 STAT GSX1 SREBP2 NFATC2 MTF1
GATA3 STAT3 GSX2 SRY NMYC MYC
GATA4 TCF4 HMGIY TCF 2-Oct MYOD
GKLF TEL2 HMX3 TFE PARP MYOGENIN
HDAC1 THAP1 HOXA1 WT1 PAX5 MZF1
HMGIY TORC2 HOXA13 ZAC PEBP2B NANOG
HNF3A USF HOXA2 ZFP641 PMX1 NEUROD
HNF3G USF2 HOXB13 ZNF333 PR NKX32
HOXA13 VMYB HOXB5 ZNF641 PRRX2 NMYC
HSF1 WT1 HOXC13 RELA NR1B2
HSF4 YY1 HOXD13 SALL2 NR2C2
IK ZBTB44 JUNB SATB1 1-Oct
ING4 ZEB1 KID3 SMAD2 OG2
IRF1 ZFP532 LBX2 SOX10 OTX
IRF7 ZFP536 LMX1A SOX17 P300
KID3 ZIC1 LRH1 SOX18 PARP
KLF ZIC3 MEF2D SPIB PAX5
KLF17 ZNF333 MEOX2 SREBP2 PEA3
LHX2 ZNF367 MIXL1 TCF1 PEBP2B
LKLF ZNF515 MSX2 TCF11 PIT1

Note: Key genes are highlighted in bold.

Abbreviation: PPi, protein–protein interaction.