Table S3.

Agreement between clinical impact evaluated by clinical assessment or by CAT (Kappa index), according to the number of criteria needed to define clinical control

Number of criteria needed to define low impact	Agreement between impact using clinical assessment or CAT (Kappa index)
	Adjustment by BODEx			Adjustment by FEV1(%)
	Global	BODEx ≤2 and CAT ≤10	BODEx ≥3 and CAT ≤16	Global	FEV1 ≥50% and CAT ≤10	FEV10 ≤49% and CAT ≤16
All criteria are met	0.43	0.52	0.28	0.42	0.51	0.28
Three criteria are met	0.37	0.22	0.61	0.45	0.39	0.58
Two criteria are met	0.21	0.11	0.40	0.19	0.12	0.37
One criterion is met	0.08	0.02	0.19	0.07	0.03	0.17

Abbreviation: CAT, COPD assessment test.