Table 1.

Initial proposal of criteria necessary to establish clinical impact

	Level of severity: mild–moderate (BODEx ≤4 points)		Level of severity: severe–very severe (BODEx >5 points)
	Low clinical impact	High clinical impact	Low clinical impact	High clinical impact
1. Clinical evaluation
Dyspnea (mMRC)	0–1	≥2	0–2	≥3
Rescue medication	≤3 times in the last week	>3 times in the last week	<2 times a day	≥2 times a day
Daily physical activitya	≥60 minutes	<60 minutes	≥30 minutes	<30 minutes
Sputum color	Absent or white	Dark	Absent or white	Dark
2. Questionnaires of clinical control (alternative evaluation)
CAT questionnaire	≤10	>10	≤20	>20
CCQ questionnaire	≤1	>1	≤2	>2

Note:

^aTime walked per day, includes the total time that the patient walked both at home and outside.

Abbreviations: CAT, COPD assessment test; CCQ, Clinical COPD Questionnaire; mMRC, Modified Medical Research Council.