Table 1. Clinicopathological features of 112 patients with metastatic breast cancer.

*Record of PR testing not available. **Date of diagnosis predates the introduction of HER2 testing in the UK.

Clinicopathologic feature	Detail	N
Age	≤ 40	9 (8%)
	> 40	103 (92%)
	Median	59
	Range	25 - 88
ER	Positive	96 (86%)
	Negative	14 (12%)
	Unknown	2 (2%)
PR	Positive	65 (58%)
	Negative	27 (24%)
	Unknown*	20 (18%)
HER2	Positive	21 (19%)
	Negative	73 (65%)
	Not tested**	18 (16%)
CA15-3	≤ 30U/ml	40 (36%)
	> 30U/ml	72 (64%)
	Median	51
	Range	1 - 3613
ALP	≤ 100 IU/L	72 (64%)
	> 100 IU/L	40 (36%)
	Median	88
	Range	30 - 555
CTCs/7.5 ml blood	0	61 (54%)
	1-4	26 (23%)
	≥5	25 (23%)
	Range	0 - 701