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Biodistribution of PLDs at different time points after a single IV injection of 10 mg/kg (A–D) or 15 mg/kg (E–I) liposomal DXR in different organs including serum (A, E), spleen and liver (B, F, and G), lungs and kidneys (C, H), and tumor (D, I) in BALB/c mice bearing C26 tumor. Data represent mean ± SE (n=4).
Abbreviations: TAT, transactivator of transcription; PLD, PEGylated liposomal doxorubicin; DXR, doxorubicin.
