Table 2.

Association between ACPA/RF status at baseline and time to first sustained remission using Cox proportional hazards regression analysis

Hazard Ratio (95% Confidence Interval), p-value
Unadjusted model	Adjusted model
ACPA status
ACPA neg/RF neg	Ref	Ref
ACPA neg /RF pos	0.86 (0.58–1.26), 0.26	0.82 (0.56–1.20), 0.31
ACPA pos /RF neg	1.28 (0.84–1.96), 0.44	1.16 (0.74–1.80), 0.52
ACPA pos /RF pos	1.42 (1.11–1.81), 0.01	1.30 (1.01–1.67), 0.04
Female	0.96 (0.74–1.23), 0.73	0.85 (0.67–1.08), 0.19
Age at baseline	0.99 (0.98–1.00), 0.02	0.99 (0.98–1.00), 0.01
CDAI at baseline	0.97 (0.96–0.98),<0.0001	0.97 (0.96–0.98),<0.0001

Adjusted model is adjusted for age, sex and CDAI at baseline.

Bold values indicate statistically significant.

ACPA, anticitrullinated protein antibody; CDAI, Clinical Disease Activity Index RF, rheumatoid factor.