Table 2.
Comparison between periods for patients with liver injuries OIS grades 4 and 5
| Period 1 n=66 |
Period 2 n=83 |
P values | |
| Age (years) | 30 (23–41) | 32 (24–50) | 0.263 |
| Blunt (%) | 65 (99) | 79 (95) | 0.266 |
| SBP (mm Hg) | 108 (85–130) | 108 (83–125) | 0.948 |
| GCS score | 14 (8–15) | 15 (9–15) | 0.623 |
| BD (mmol/L) | 3.9 (1.7–9.4) | 4.0 (1.7–8.1) | 0.898 |
| ISS | 34 (25–45) | 34 (26–48) | 0.444 |
| Liver injury grade, n (%) | |||
| OIS grade 4 | 51 (77) | 61 (73) | 0.596 |
| OIS grade 5 | 15 (23) | 22 (27) | |
| Patients transfused, n (%) | 25 (38) | 33 (40) | 0.815 |
| Infusions first 24 hours among transfused | |||
| RBCs, units | 10 (4–27) | 9 (7–24) | 0.677 |
| Plasma, units | 4 (1–11) | 13 (8–20) | <0.001 |
| Platelets*, units | 2 (0–5) | 3 (1–4) | 0.275 |
| Plasma:RBC ratio | 0.39 (0.21–0.55) | 1.04 (0.72–1.50) | <0.001 |
| Crystalloids, L | 5.0 (4.0–10.5) | 1.7 (1.0–3.0) | <0.001 |
| NOM, n (%) | 45 (68) | 58 (70) | 0.860 |
| FNOM, n (%) | 2 (4) | 0 (0) | 0.195 |
| Angiography, n (%) | 44 (68) | 18 (22) | <0.001 |
| AE liver, n (%) | 20 (30) | 10 (12) | 0.006 |
| 30-day mortality, n (%) | 11 (17) | 12 (15) | 0.711 |
| OIS grade 4, n (%) | 4/51 (8) | 6/61 (10) | 0.996 |
| OIS grade 5, n (%) | 7/15 (47) | 6/22 (27) | 0.406 |
| Death from hemorrhage, n (%) | 9 (14) | 5 (6) | 0.158 |
| Liver-related hemorrhagic death, n (%) | 7 (11) | 3 (4) | 0.109 |
Values are given as median (IQR) where not stated otherwise.
*Each unit of platelets contains platelets from four donors.
AE, angioembolization; BD, base deficit; FNOM, failure of non-operative management; GCS, Glasgow Coma Scale; ISS, Injury Severity Score; NOM, non-operative management; OIS, Organ Injury Scale; RBCs, red blood cells; SBP, systolic blood pressure.