Table 3.
Baseline characteristics of men and women with HFpEF and HFrEF
| Variable | HFpEF | HFrEF | |||
| Men (n=1879) |
Women (n=873) |
Men (n=3726) |
Women (n=1090) | P values* | |
| Age (mean±SD) | 68.57±9.50 | 71.41±8.65 | 67.54±10.01 | 69.58±9.43 | <0.001 |
| 40–64 | 619 (32.9%) | 196 (22.5%) | 1406 (37.7%) | 324 (29.7%) | <0.001 |
| 65–74 | 698 (37.1%) | 317 (36.3%) | 1291 (34.6%) | 389 (35.7%) | |
| 75–84 | 518 (27.6%) | 325 (37.2%) | 930 (25.0%) | 334 (30.6%) | |
| ≥85 | 44 (2.3%) | 35 (4.0%) | 99 (2.7%) | 43 (3.9%) | |
| Rurality | 282 (15.0%) | 121 (13.9%) | 532 (14.3%) | 153 (14.0%) | 0.64 |
| Income quintile 1 (lowest) | 346 (18.4%) | 238 (27.3%) | 800 (21.5%) | 261 (23.9%) | <0.001 |
| 2 | 422 (22.5%) | 192 (22.0%) | 810 (21.7%) | 244 (22.4%) | |
| 3 | 387 (20.6%) | 165 (18.9%) | 738 (19.8%) | 204 (18.7%) | |
| 4 | 380 (20.2%) | 152 (17.4%) | 669 (18.0%) | 208 (19.1%) | |
| 5 (highest) | 334 (17.8%) | 125 (14.3%) | 687 (18.4%) | 161 (14.8%) | |
| Missing | 10 (0.5%) | ≤5 (0.1%) | 22 (0.6%) | 12 (1.1%) | |
| Remote MI | 632 (33.6%) | 285 (32.6%) | 1618 (43.4%) | 454 (41.7%) | <0.001 |
| Recent MI | 920 (49.0%) | 498 (57.0%) | 2444 (65.6%) | 811 (74.4%) | <0.001 |
| Previous PCI | 387 (20.6%) | 155 (17.8%) | 599 (16.1%) | 177 (16.2%) | <0.001 |
| Hypertension | 1766 (94.0%) | 844 (96.7%) | 3395 (91.1%) | 1032 (94.7%) | <0.001 |
| Atrial fibrillation | 301 (16.0%) | 132 (15.1%) | 653 (17.5%) | 138 (12.7%) | 0.001 |
| Cerebrovascular disease | 283 (15.1%) | 130 (14.9%) | 514 (13.8%) | 161 (14.8%) | 0.56 |
| Peripheral vascular disease | 389 (20.7%) | 190 (21.8%) | 801 (21.5%) | 246 (22.6%) | 0.69 |
| COPD/Asthma | 717 (38.2%) | 373 (42.7%) | 1345 (36.1%) | 445 (40.8%) | <0.001 |
| Diabetes | 1083 (57.6%) | 543 (62.2%) | 2261 (60.7%) | 761 (69.8%) | <0.001 |
| Morbid obesity | 710 (37.8%) | 244 (27.9%) | 1235 (33.1%) | 303 (27.8%) | <0.001 |
| Hypothyroidism | 29 (1.5%) | 41 (4.7%) | 47 (1.3%) | 31 (2.8%) | <0.001 |
| Anaemia | 185 (9.8%) | 133 (15.2%) | 355 (9.5%) | 137 (12.6%) | <0.001 |
| Dialysis | 128 (6.8%) | 49 (5.6%) | 205 (5.5%) | 63 (5.8%) | 0.26 |
| Chronic renal disease | 242 (12.9%) | 106 (12.1%) | 478 (12.8%) | 129 (11.8%) | 0.79 |
| Liver disease | 26 (1.4%) | 12 (1.4%) | 55 (1.5%) | 15 (1.4%) | 0.99 |
| Primary tumour | 133 (7.1%) | 51 (5.8%) | 231 (6.2%) | 67 (6.1%) | 0.52 |
| Metastatic tumour | 14 (0.7%) | ≤5 (0.2%) | 24 (0.6%) | 14 (1.3%) | 0.04 |
| Dementia | 14 (0.7%) | 6 (0.7%) | 13 (1.2%) | 24 (0.6%) | 0.326 |
| Frailty | 538 (28.6%) | 360 (41.2%) | 1022 (27.4%) | 447 (41.0%) | <0.001 |
| Emergent surgery | 107 (5.7%) | 62 (7.1%) | 431 (11.6%) | 159 (14.6%) | <0.001 |
*P values were obtained using one-way analysis of variance test for means and χ2 test for categorical variables.
COPD, chronic obstructive pulmonary disease; HFpEF, heart failure with preserved ejection fraction;HFrEF, heart failure with reduced ejection fraction;MI, myocardial infarction;PCI, percutaneous coronary intervention.