Table 2.

Ventilator settings, ventilation and transcutaneous blood gas values at baseline, presurfactant and at extubation time

	Extubation Success Group	Extubation Failure Group	P values
Baseline
MAP (cm H2O)	10.2±1.1	10.2±1.0	0.94
FiO2	0.40±0.17	0.48±0.24	0.08
Amplitude (%)	59±33	56±32	0.72
Frequency (Hz)	9.6±1.0	9.7±0.8	0.69
VT (mL/kg)	1.6±0.6	1.5±0.5	0.51
DCO2 (mL2/kg2/s)	25±15	25±10	1
TcPO2 (mm Hg)	53±12	50±8	0.31
TcPCO2 (mm Hg)	52±8	54±4	0.30
Presurfactant
MAP (cm H2O)	13.1±1.6	11.9±2.4	0.02
FiO2	0.25±0.01	0.33±0.08	<0.001
Amplitude (%)	76±30	62±31	0.08
Frequency (Hz)	9.3±1.0	9.6±0.9	0.30
VT (mL/kg)	1.9±0.6	1.8±0.4	0.52
DCO2 (mL2/kg2/s)	29±15	29±10	1
TcPO2 (mm Hg)	59±16	54±11	0.23
TcPCO2 (mm Hg)	46±9	50±4	0.08
Extubation
MAP (cm H2O)	6.1±0.9	6.1±1.2	0.97
FiO2	0.22±0.03	0.23±0.02	0.30
Amplitude (%)	43±24	39±12	0.46
Frequency (Hz)	9.3±1.2	9.3±0.7	0.88
VT (mL/kg)	2.1±0.6	1.9±0.6	0.28
DCO2 (mL2/kg2/s)	34±11	35±15	0.70
TcPO2 (mm Hg)	56±5	54±3	0.08
TcPCO2 (mm Hg)	48±3	49±2	0.18

Values expressed as mean±SD.

DCO₂, coefficient of gas transport; MAP, mean airways pressure; TcPCO₂, transcutaneous PaO2 of CO₂; TcPO₂, transcutaneous PaO2 of O₂.V_T: tidal volume HFOV.