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(A) Inhibition of autophagosome formation by TAT-HA-Atg5K130R abolishes CAP-induced cardioprotection (B) Inhibition of autophagosome formation (K130R) abolishes the CAP induced CK activity reduction in perfused rat hearts. n=3-8 (C) The effect of CAP on autophagy-related protein LC3 levels in isolated hearts n=3 *p <0.05 vs. CON Data are presented as means ± SEM. Chloramphenicol - CAP, Chloroquine – CQ, Control - CON, TAT-HA-Atg5K130R - K130R, Creatine kinase – CK
