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. 2018 Nov 19;13(11):e0207740. doi: 10.1371/journal.pone.0207740

Table 1. Characteristics of study participants.

N Admission P-value N All-cause mortality P-value Suicide mortality P-value
No Yes No Yes No Yes
COC measure
    Low 152 125 (82.2) 27 (17.8) < .0001 152 138 (90.8) 14 (9.2) 0.017 145 (95.4) 7 (4.6) < .0001
    Medium 4273 3994 (93.5) 279 (6.5) 4308 3994 (92.7) 314 (7.3) 4202 (97.5) 106 (2.5)
    High 44133 43238 (98.0) 895 (2.0) 44487 41676 (93.7) 2811 (6.3) 44082 (99.1) 405 (0.9)
Outpatient visits
    Low 9602 9495 (98.9) 107 (1.1) < .0001 9680 9159 (94.6) 521 (5.4) < .0001 9620 (99.4) 60 (0.6) < .0001
    High 38956 37862 (97.2) 1094 (2.8) 39267 36649 (93.3) 2618 (6.7) 38809 (98.8) 458 (1.2)
Diagnosis
    Unipolar disorder 46708 45694 (97.8) 1014 (2.2) < .0001 47073 44088 (93.7) 2985 (6.3) 0.0011 46592 (99.0) 481 (1.0) < .0001
    Bipolar disorder 1850 1663 (89.9) 187 (10.1) 1874 1720 (91.8) 154 (8.2) 1837 (98.0) 37 (2.0)
Age
    20–39 15522 15082 (97.2) 440 (2.8) 0.0058 15550 15333 (98.6) 217 (1.4) < .0001 15419 (99.2) 131 (0.8) 0.0006
    40–59 18830 18394 (97.7) 436 (2.3) 18913 18341 (97.0) 572 (3.0) 18718 (99.0) 195 (1.0)
    60–79 12849 12553 (97.7) 296 (2.3) 13041 11262 (86.4) 1779 (13.6) 12866 (98.7) 175 (1.3)
    80 or above 1357 1328 (97.9) 29 (2.1) 1443 872 (60.4) 571 (39.6) 1426 (98.8) 17 (1.2)
Sex
    Men 15224 14838 (97.5) 386 (2.5) 0.5513 15430 13895 (90.1) 1535 (10.0) < .0001 15165 (98.3) 265 (1.7) < .0001
    Women 33334 32519 (97.6) 815 (2.4) 33517.0 31913 (95.2) 1604 (4.8) 33264 (99.3) 253 (0.8)
Income
    Low 14067 13772 (97.9) 295 (2.1) 0.0029 14182 13272 (93.6) 910 (6.4) < .0001 14044 (99.0) 138 (1.0) 0.4335
    Middle 19069 18571 (97.4) 498 (2.6) 19205 18125 (94.4) 1080 (5.6) 18990 (98.9) 215 (1.1)
    High 15422 15014 (97.4) 408 (2.7) 15560 14411 (92.6) 1149 (7.4) 15395 (98.9) 165 (1.1)
Region
    Seoul 10337 10086 (97.6) 251 (2.4) 0.5887 10420 9805 (94.1) 615 (5.9) 0.0296 10310 (98.9) 110 (1.1) 0.8587
    Urban 11815 11535 (97.6) 280 (2.4) 11909 11154 (93.7) 755 (6.3) 11788 (99.0) 121 (1.0)
    Rural 26406 25736 (97.5) 670 (2.5) 26618 24849 (93.4) 1769 (6.7) 26331 (98.9) 287 (1.1)
Antidepressant
    No 44936 43799 (97.5) 1137 (2.5) 0.0044 45306 42363 (93.5) 2943 (6.5) 0.0084 44813 (98.9) 493 (1.1) 0.0227
    Yes 3622 3558 (98.2) 64 (1.8) 3641 3445 (94.6) 196 (5.4) 3616 (99.3) 25 (0.7)
Antipsychotic
    No 48296 47105 (97.5) 1191 (2.5) 0.1603 48680 45554 (93.6) 3126 (6.4) 0.3017 48163 (98.9) 517 (1.1) 0.2736
    Yes 262 252 (96.2) 10 (3.8) 267 254 (95.1) 13 (4.9) 266 (99.6) 1 (0.4)
Anxiolytic
    No 45728 44598 (97.5) 1130 (2.5) 0.9003 46089 43148 (93.6) 2941 (6.4) 0.2469 45604 (99.0) 485 (1.1) 0.6039
    Yes 2830 2759 (97.5) 71 (2.5) 2858 2660 (93.1) 198 (6.9) 2825 (98.9) 33 (1.2)
Stabilizer
    No 48302 47116 (97.5) 1186 (2.5) 0.0005 48690 45574 (93.6) 3116 (6.4) 0.0961 48178 (99.0) 512 (1.1) 0.0450
    Yes 256 241 (94.1) 15 (5.9) 257 234 (91.1) 23 (9.0) 251 (97.7) 6 (2.3)
Psychotherapy
    None 29408 28710 (97.6) 698 (2.4) 0.0212 29653 27842 (93.9) 1811 (6.1) < .0001 29381 (99.1) 272 (0.9) < .0001
    Personal therapy 18530 18053 (97.4) 477 (2.6) 18668 17410 (93.3) 1258 (6.7) 18432 (98.7) 236 (1.3)
    Group therapy 512 491 (95.9) 21 (4.1) 518 460 (88.8) 58 (11.2) 513 (99.0) 5 (1.0)
    Others 108 103 (95.4) 5 (4.6) 108 96 (88.9) 12 (11.1) 103 (95.4) 5 (4.6)
Charlson Comorbidity Index
    0 33010 32177 (97.5) 833 (2.5) 0.3346 33223 31622 (95.2) 1601 (4.8) < .0001 32895 (99.0) 328 (1.0) 0.0155
    1 5419 5288 (97.6) 131 (2.4) 5478 4968 (90.7) 510 (9.3) 5420 (98.9) 58 (1.1)
    2 6559 6419 (97.9) 140 (2.1) 6621 6120 (92.4) 501 (7.6) 6541 (98.8) 80 (1.2)
    3 2553 2482 (97.2) 71 (2.8) 2594 2251 (86.8) 343 (13.2) 2551 (98.3) 43 (1.7)
    4+ 1017 991 (97.4) 26 (2.6) 1031 847 (82.2) 184 (17.9) 1022 (99.1) 9 (0.9)
Type of medical institution
    Tertiary hospital 12797 12163 (95.1) 634 (5.0) < .0001 12941 11859 (91.6) 1082 (8.4) < .0001 12721 (98.3) 220 (1.7) < .0001
    Secondary hospital 3514 3357 (95.5) 157 (4.5) 3567 3250 (91.1) 317 (8.9) 3523 (98.8) 44 (1.2)
    Primary clinic 32247 31837 (98.7) 410 (1.3) 32439 30699 (94.6) 1740 (5.4) 32185 (99.2) 254 (0.8)
Total 48558 47357 (97.5) 1201 (2.5) 48947 45808 (93.6) 3139 (6.4) 48429 (98.9) 518 (1.1)