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. 2018 Nov 19;13(11):e0207740. doi: 10.1371/journal.pone.0207740

Table 2. Factors associated with hospital admissions, all-cause mortality, and suicide mortality.

Admission* All-cause* Suicide*
OR 95% CI HR 95% CI HR 95% CI
COC measure
    Low 1.00 1.00 1.00
    Medium 0.30 (0.19 - 0.47) 1.16 (0.68 - 1.98) 0.74 (0.34 - 1.61)
    High 0.14 (0.09 - 0.21) 1.14 (0.67 - 1.94) 0.35 (0.16 - 0.74)
Outpatient visits
    Low 1.00 1.00 1.00
    High 2.04 (1.66 - 2.50) 1.06 (0.96 - 1.16) 1.51 (1.14 - 1.99)
Diagnosis
    Unipolar disorder 1.00 1.00 1.00
    Bipolar disorder 3.56 (2.99 - 4.23) 1.31 (1.11 - 1.54) 1.40 (0.99 - 1.99)
Age
    20–39 1.00 1.00 1.00
    40–59 0.80 (0.70 - 0.92) 2.10 (1.80 - 2.46) 1.18 (0.94 - 1.48)
    60–79 0.74 (0.63 - 0.87) 10.49 (9.08 - 12.12) 1.69 (1.33 - 2.15)
    80 or above 0.72 (0.49 - 1.07) 48.45 (41.24 - 56.93) 2.08 (1.23 - 3.53)
Sex
    Men 1.00 1.00 1.00
    Women 1.09 (0.96 - 1.23) 0.45 (0.42 - 0.48) 0.42 (0.35 - 0.50)
Income
    Low 1.00 1.00 1.00
    Middle 1.21 (1.04 - 1.40) 0.86 (0.78 - 0.94) 1.09 (0.88 - 1.35)
    High 1.23 (1.05 - 1.44) 0.83 (0.76 - 0.91) 0.95 (0.75 - 1.19)
Region
    Seoul 1.00 1.00 1.00
    Urban 1.03 (0.87 - 1.23) 1.13 (1.01 - 1.25) 1.02 (0.79 - 1.34)
    Rural 1.09 (0.93 - 1.26) 1.06 (0.96 - 1.16) 1.08 (0.86 - 1.35)
Antidepressant
    No 1.00 1.00 1.00
    Yes 0.69 (0.53 - 0.89) 0.82 (0.71 - 0.96) 0.70 (0.47 - 1.06)
Antipsychotic
    No 1.00 1.00 1.00
    Yes 0.64 (0.33 - 1.23) 0.59 (0.34 - 1.02) 0.24 (0.03 - 1.71)
Anxiolytic
    No 1.00 1.00 1.00
    Yes 0.86 (0.67 - 1.10) 0.94 (0.81 - 1.08) 0.98 (0.68 - 1.41)
Stabilizer
    No 1.00 1.00 1.00
    Yes 0.92 (0.53 - 1.61) 1.54 (1.02 - 2.32) 1.53 (0.67 - 3.47)
Psychotherapy
    None 1.00 1.00 1.00
    Personal therapy 0.99 (0.88 - 1.12) 0.98 (0.91 - 1.06) 1.17 (0.98 - 1.39)
    Group therapy 2.03 (1.29 - 3.20) 1.45 (1.11 - 1.88) 1.06 (0.44 - 2.58)
    Others 1.46 (0.58 - 3.69) 1.21 (0.68 - 2.14) 4.15 (1.70 - 10.13)
Charlson Comorbidity Index
    0 1.00 1.00 1.00
    1 0.91 (0.75 - 1.11) 1.16 (1.05 - 1.28) 0.92 (0.69 - 1.22)
    2 0.85 (0.70 - 1.02) 0.97 (0.88 - 1.08) 1.03 (0.80 - 1.33)
    3 1.11 (0.86 - 1.44) 1.29 (1.14 - 1.45) 1.25 (0.89 - 1.75)
    4+ 1.10 (0.73 - 1.65) 1.50 (1.29 - 1.76) 0.67 (0.34 - 1.30)
Type of medical institution
    Tertiary hospital 1.00 1.00 1.00
    Secondary hospital 0.94 (0.78 - 1.13) 1.08 (0.95 - 1.23) 0.78 (0.56 - 1.10)
    Primary clinic 0.28 (0.25 - 0.32) 0.73 (0.68 - 0.79) 0.53 (0.44 - 0.64)
Year 0.96 (0.95 - 0.98) - -

*Adjusted for frequency of outpatient visits, age, sex, income, region, antidepressant, antipsychotic, anxiolytic, stabilizer, treatment type, CCI, year, medical institution type, and disease type

†Other psychotherapy includes continuous sleep therapy and psychiatric social work