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. 2018 Nov 15;72(4):739–752.e9. doi: 10.1016/j.molcel.2018.09.028

Figure 1.

Figure 1

The UBL Domain of UHRF1 Contacts Other Regions within the Protein

(A) Schematic of full-length mouse UHRF1 (Np95) indicating domain architecture and function. Red lines indicate known intra-molecular interactions.

(B) Crosslinking with mass spectrometry (XL-MS) profile of UHRF1. Crosslinks involving the UBL domain are shown in purple and other intra-protein crosslinks in red. Individual domains within UHRF1 are annotated.

(C) Proposed model of UHRF1 folding.