The UBL Domain of UHRF1 Contacts Other Regions within the Protein
(A) Schematic of full-length mouse UHRF1 (Np95) indicating domain architecture and function. Red lines indicate known intra-molecular interactions.
(B) Crosslinking with mass spectrometry (XL-MS) profile of UHRF1. Crosslinks involving the UBL domain are shown in purple and other intra-protein crosslinks in red. Individual domains within UHRF1 are annotated.
(C) Proposed model of UHRF1 folding.