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. 2018 Nov 15;72(4):636–649.e8. doi: 10.1016/j.molcel.2018.08.042

Figure 7.

Figure 7

Model for ZMYND8 Function in Igh Gene Diversification

ZMYND8 controls both CSR and Igh SHM via its ability to regulate the activity of the 3′ Igh super-enhancer. GTL for S-Cγ1 is representative of acceptor S region induction.