Skip to main content
. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2018 Sep 25;139:10–18. doi: 10.1016/j.prostaglandins.2018.09.005

Figure 3. Regulation of platelet function and thrombosis by ω-3 and ω-6 PUFAs.

Figure 3.

PUFAs are an essential component of the platelet phospholipid membrane with the main ω-3 and ω-6 PUFAs being oxygenated by two important oxygenases (COX-1 and 12-LOX) to produce oxylipins in platelets. ω-3 and ω-6 PUFA oxylipin metabolites will further contribute to the regulation of platelet function in hemostasis and thrombosis.