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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Mol Cell Neurosci. 2018 Sep 22;93:1–9. doi: 10.1016/j.mcn.2018.09.002

Figure 6: CAW increases mitochondrial, antioxidant and synaptic proteins in the hippocampus and cortex of 5×FAD mice.

Figure 6:

Synaptic gene expression was reduced in 5×FAD mice in the hippocampus (A) and frontal cortex (B) but this was attenuated by CAW treatment. CAW treatment also increased expression of NRF2 and its ARE-containing target genes in the hippocampus (C) and frontal cortex (D) of both 5×FAD and WT animals. 5×FAD mice had a reduction in expression of ETC genes in the hippocampus (E) and frontal cortex (F) and CAW treatment increased this expression in both brain regions. n=8-10, *p<0.05, **p<0.01, ***p<0.001.