Table 2.

Medial elastic fiber thickness and wall shear stress (WSS) averaged in healthy volunteers and BAV patients. Data stratified between circumferential locations, aortic valve stenosis (AS) and aorta diameter. For each, n denotes the total number of measurements.

Healthy volunteers	Measurements, n	Elastic fiber thickness (μm), median (interquartile range)	WSS (Pa), median (interquartile range)
Anterior wall	40	-	0.55 (0.42–0.73)
Posterior wall	40	-	0.64 (0.55–0.72)
Greater curvature	40	-	0.60 (0.44–0.67)‡
Lesser curvature	40	-	0.63 (0.51–0.84)
All BAV patients
Anterior wall	25	3.08 (2.72–3.29)	0.78 (0.62–0.96)
Posterior wall	23	2.95 (2.67–3.13)	1.35 (0.88–1.66)*, ‡
Greater curvature	30	2.71 (2.56–2.88)*, ‡	1.20 (0.99–1.38)*, ‡
Lesser curvature	15	3.10 (2.93–3.25)	0.77 (0.62–1.02)
BAV subgroups according to aortic valve stenosis (AS)
AS (AR or no-AR)	73	2.94 (2.67–3.13)	1.10 (0.76–1.46)
no AS (predominant AR)	20	2.76 (2.54–3.16)	0.93 (0.78–1.14)
BAV subgroups according to maximal aorta diameter (cm)
< 4.5	33	2.94 (2.69–3.20)	0.99 (0.77–1.37)
4.5 – 5	42	2.95 (2.66–3.12)	1.01 (0.77–1.33)
≥ 5	18	2.70 (2.56–3.02)	1.14 (0.78–1.45)

AR: aortic valve regurgitation

^*p<0.05 for comparison against A;

^‡against LC regions, within healthy volunteers and patients groups.

Bold numbers indicate p<0.05 against healthy volunteers.