Fig. 4.

CED-1-overexpressing muscle-type engulfing cells adhere AVM axons and PVD dendrites. Representative images showing wild-type AVM axons (a), unc-6 mutant AVM axons (b), wild-type PVD dendrites (d), and sax-7 mutant PVD dendrites (e). AVM axons (c) and PVD dendrites (f) without their respective guidance cues, unc-6 (netrin) and sax-7 (L1CAM), were redirected and adhered to muscles expressing CED-1. AVM neurons were labeled by zdIs5[Pmec-4::GFP] and PVD neurons were labeled by xrIs37[PF49H12.4::GFP]. The dashed box area in (f) was blown up and shown in (g). Arrowheads in (c), (f), and (g) indicate muscle contacts. Anterior is to the left, dorsal is up. Scale bar, 20 μm