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. 2018 Nov 19;9:4857. doi: 10.1038/s41467-018-06488-4

Table 1.

Antibacterial activitya expressed in MICs and cytotoxicity over Caco-2 cells expressed in IC50 (MTT assay)

Compound Nr MIC (µM) Cytotoxicity IC50 (µM)
B. anthracis E. faecalis B. cereus 24 h 48 h
Sterne Pathogenic Ovine
1 25 25 25 50 25 100 > 50
2 24 48 48 > 48 48 > 50 > 50
3 27 54 54 > 54 27 > 100 100
4 25 25 25 > 50 25 100 50
5 202 101 101 101 202 n.d. n.d.
6 24 24 48 48 n.d. n.d. n.d.
7 26 52 52 52 n.d > 100 100
8 26 26 52 52 n.d. n.d. n.d.
9 50 50 50 50 25 100 50
10 27 27 27 > 54 27 > 100 > 100
11 12.6 12.6 12.6 12.6 12.6 n.d. 50
12 > 405 > 405 > 405 > 405 > 405 n.d. 50
13 386 12.0 12.0 12.0 386 100 > 50
14 104 51 51 51 51 n.d. n.d.
15 51 51 51 51 51 n.d. n.d.
16 24 24 > 48 > 48 48 n.d. n.d.
17 26 52 52 > 52 52 > 100 > 100
18 26 26 52 52 52 > 100 > 50
19 50 25 50 50 25 n.d. n.d.
20 25 50 50 > 50 50 n.d. n.d.
21 28 28 28 56 28 > 100 100
Ref.b 25 25 25 19 19 n.d. n.d.

aMüller–Hinton agar dilution method following CLSI guidelines15. bChloramphenicol