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. 2018 Nov 19;9(12):1144. doi: 10.1038/s41419-018-1196-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The proportion of the indicated NSN and SN nucleolus types in PD21 ovaries showing that most of the oocytes in Rps26^fl/fl/Gdf9-Cre mice were NSN type. b Protein levels of the trimethylation of H3K4 (H3K4me3) and H3K9 (H3K9me3) were significantly decreased in the GV oocytes of the Rps26^fl/fl/Gdf9-Cre mice compared to the levels in Rps26^fl/fl mice. c–d Immunofluorescence of H3K4me3 (c) and H3K9me3 (d) in PD21 GV oocytes (SN and NSN types) showing that low levels of H3K4me3 and H3K9me3 in Rps26^fl/fl/Gdf9-Cre mice correlated with the high proportion of NSN type oocytes