Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 19;9(12):1144. doi: 10.1038/s41419-018-1196-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a–c The mRNA expressions of Pi3k3ca (a), Pi3k3cb (b), and Pik3cd (c) were decreased in oocytes from PD14 Rps26^fl/fl/Gdf9-Cre (RGC) mice compared to control (CTRL) Rps26^fl/fl mice, as analyzed by RNA sequencing. *p < 0.05 as calculated by two-tailed Student’s t-tests. d, f The mRNA expressions of Pten (d) and Foxo3a (f) were increased in Rps26^fl/fl/Gdf9-Cre (RGC) mice compared to control (CTRL) Rps26^fl/fl mice. *p < 0.05 as calculated by two-tailed Student’s t-tests. e The mRNA expression of Akt was decreased in oocytes of Rps26^fl/fl/Gdf9-Cre (RGC) mice compared to control (CTRL) Rps26^fl/fl mice. g Western blot results showing the expression of p-Akt (Ser473), Akt, p-Foxo3a (Ser253), Foxo3a, p-Rps6 (Ser235/236), and Rps6 in the oocytes from Rps26^fl/fl/Gdf9-Cre (RGC) mice and control (CTRL) Rps26^fl/fl mice at the age of PD12–14. h Western blot results showing reduced expression of the p-Akt (Ser473), p-Foxo3a (Ser253), p-Rps6 (Ser235/236), and Rps6 proteins and increased expression of the Foxo3a and P27 proteins in the PD12–14 ovaries of Rps26^fl/fl/Gdf9-Cre (RGC) mice compared to control (CTRL) Rps26^fl/fl mice