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. 2018 Nov 13;5:317. doi: 10.3389/fmed.2018.00317

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Copyright © 2018 Eisinger, Patzelt and Langer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Platelets in bacterial and viral infections. The role of platelets in infections may be underestimated. Platelets were shown to have a significant part in infectious diseases such as viral hepatitis, malaria, and listeriosis. Bct, bacteria; CD40L, cluster of differentiation 40 ligand; C3, complement component 3; cT-Cell, cytotoxic T-cell; DC, dendritic cell; GPIbα, glycoprotein Ibα; 5HT-R, 5-hydroxytryptamine-receptor; IL8, interleukin 8; LPS, lipopoly-saccharides; MAC, membrane attack complex; PF4, platelet factor 4; P-sel, P-selectin; RBC, red blood cell; ROS, reactive oxygen species; Ser, serotonin; Tcd 1/2, thrombocidin 1/2; TLR4, toll like receptor 4; TREM1, triggering receptor expressed on myeloid cells 1.