Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 13;5:317. doi: 10.3389/fmed.2018.00317

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Eisinger, Patzelt and Langer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Platelets as regulators of angiogenesis. Platelets are able to both stimulate and inhibit the process of angiogenesis due to a variety of mediators stored in their granules. Furthermore, platelets are suggested to recruit circulating regenerative cells to the site of vascular lesion supported by soluble mediators. How these cells then contribute to tissue remodeling is still a matter of debate. BM-PC, bone marrow derived progenitor cells; bFGF, basic fibroblast growth factor, EC, endothelial cell; EGF, epidermal growth factor; HGF, hepatocyte growth factor; MMPs, matrix metalloproteinases; PDGF, platelet derived growth factor; PF4, platelet factor 4; P-sel, P-selectin; PSGL1, P-selectin glycoprotein ligand-1; PTL, platelet; S1P, sphingosine-1-phosphate; SDF-1, stromal cell-derived factor 1; TIMPs, tissue inhibitors of matrix metalloproteinases; TSP-1, thrombospondin 1; VEGF, vascular endothelial growth factor.