Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 13;9:1297. doi: 10.3389/fphar.2018.01297

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Li, Liu, Yang, Xu, Lv, Zhang, Liu, Zhang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of N-myristoylation of CM4 on the structure and cytotoxicity to breast cancer cells and normal cells. (A) Secondary structure analysis by CD spectroscopy. Far-UV CDspectra were conducted at room temperature in TFE/water mixtures at 50% (v/v). Peptide concentration was 250 μg/mL. (B) Comparison of the cell viability of three breast cell lines and two normal cell lines after treated by different concentration of myristoyl-CM4 and CM4 by MTT assay. (C) Hemolytic activity was tested by mouse erythrocytes. Melittin was used as a control. All assays were performed as described in section 2. Results are mean ± SEM of 4–6 different experiments.