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. 2018 Nov 13;9:2608. doi: 10.3389/fimmu.2018.02608

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Copyright © 2018 Xie, Sun, Wu, Huang, Jin, Guo, Zhang, Liu, Liu, Cao, Wang and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maternal high fat diet altered the β diversity of gut microbiota and the key bacterial alterations in 3-week old offspring mice. Total fecal bacteria from each 3-week old offspring mice were detected by 16S rRNA sequencing. Beta diversity (A), Unweighted Unifrac ANOSIM analysis between two groups (B) and differentially abundant species at the phylum, class, order, family, and genus level in Cladogram generated by LEfSe analysis (C) was shown. MHFD, maternal high fat diet. MCD, maternal control diet. In (A–C), n = 10 in each group.