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. 2018 Nov 13;9:2608. doi: 10.3389/fimmu.2018.02608

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Copyright © 2018 Xie, Sun, Wu, Huang, Jin, Guo, Zhang, Liu, Liu, Cao, Wang and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maternal high fat diet altered the composition and diversity of gut microbiota in 8-week old offspring mice. Mice were treated as described in Figure 1A and total fecal bacteria from each 8-week old offspring mice were detected by 16S rRNA sequencing. Venn diagram (A), the relative abundance of bacterial taxa at the phylum level between two groups (B), Shannon and Simpson diversity index (C) was shown. Beta diversity was measured by Unweighted UniFrac distance (D). MHFD, maternal high fat diet. MCD, maternal control diet. In (A–D), n = 6 in MHFD 8 w group, n = 8 in MCD 8 w group.