Table 3.
Seed ROIs | Region | BA | Cluster size | MNI coordinate |
T-value | ||
---|---|---|---|---|---|---|---|
X | Y | Z | |||||
ASD > TD | |||||||
Left Crus I | Left insula | 13 | 144 | –40 | –12 | 18 | 5.44 |
Left supramarginal gyrus | –52 | –24 | 20 | 4.11 | |||
Left Crus II | Right middle frontal gyrus | 229 | 16 | 40 | –20 | 4.85 | |
Right inferior frontal gyrus | 11 | 24 | 36 | –20 | 4.79 | ||
Right inferior frontal gyrus | 14 | 22 | –18 | 4.61 | |||
Right Crus II | Left supramarginal gyrus | 40 | 89 | –62 | –24 | 14 | 4.78 |
Left supramarginal gyrus | –54 | –22 | 20 | 4.03 | |||
Vermis VIIIa | Right angular gyrus | 40 | 117 | 38 | –58 | 42 | 5.98 |
Right angular gyrus | 32 | –52 | 38 | 5.25 | |||
Vermis VIIIb | Right supramarginal gyrus | 40 | 183 | 42 | –42 | 42 | 5.16 |
Right inferior parietal lobule | 38 | –54 | 42 | 4.54 | |||
Vermis X | Right middle temporal gyrus | 112 | 66 | –32 | –18 | 5.53 | |
ASD < TD | |||||||
Right lobule IX | Right cerebellar lobule VI | 78 | 32 | –56 | –34 | 4.91 | |
Vermis VI | Left middle frontal gyrus | 381 | –22 | 18 | 52 | 6.31 | |
Left middle frontal gyrus | 8 | –32 | 28 | 46 | 5.34 | ||
Left middle frontal gyrus | 8 | –24 | 24 | 46 | 4.45 | ||
Left inferior temporal gyrus | 96 | –52 | –34 | –20 | 4.26 | ||
Left middle temporal gyrus | –56 | –38 | –14 | 3.97 | |||
Right medial frontal gyrus | 8 | 72 | 6 | 26 | 46 | 4.70 | |
Right medial frontal gyrus | 9 | 4 | 34 | 38 | 4.60 | ||
Right dentate nucleus | Left inferior frontal gyrus | 105 | –20 | 34 | –24 | 5.61 | |
Left inferior frontal gyrus | 47 | –18 | 16 | –24 | 3.75 | ||
Left inferior parietal lobule | 40 | 85 | –48 | –48 | 54 | 4.29 | |
Left inferior parietal lobule | 40 | –54 | –42 | 52 | 4.07 | ||
Left inferior parietal lobule | 40 | –56 | –50 | 46 | 4.03 |
ASD, autism spectrum disorder; TD, typically developing controls; MNI, Montreal Neurological Institute; BA, Brodmann area.
Regions in bold font indicate the peak voxel in a particular cluster. All results are reported using a voxel-height threshold at uncorrected p < 0.001 with cluster-extent threshold at false discovery rate-corrected p < 0.05.