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. 2018 Nov 13;9:1306. doi: 10.3389/fphar.2018.01306

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Copyright © 2018 Lee, Coelho, Class, Sern, Bocz and Szumlinski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of intra-AcbSh MTEP and adolescent-onset alcohol consumption upon behavior in the forced swim test. (A) No significant group differences were observed regarding the time adolescent mice spent immobile in the forced swim test. (B) Overall, alcohol-drinking mice exhibited a shorter latency to their first immobile episode, compared to water-drinking controls, with a significant group difference observed for the vehicle-infused mice only. MTEP did not affect this measure, irrespective of drinking history. (C) There were no group differences in the total number of immobile episodes. ^∗p < 0.05 drinking effect within same intracranial treatment group.