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. 2018 Nov 13;11:388. doi: 10.3389/fnmol.2018.00388

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Copyright © 2018 Ren, Yu, Wu, Si, Li, Liu, Zhou, Deng and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ICV injection of miRNA-210 antagomir effectively restore hippocampal snap25 expression in VD model (n = 6/group). (A) miR-210-5p and Snap25 mRNA expression detected by qPCR (n = 6/group). (B) Snap25 protein expression visualized through immunofluorescence. (C) Snap 25 protein expression in hippocampus tested by western blot (n = 6/group). Data are shown as mean ± SD values, and statistical significance between both groups is defined as *p < 0.05; **p < 0.01.