Table 3.
Hyperfibrinolysis scores in dogs (n = 6 per group) with hemorrhagic shock given 20 mL kg−1 of either fresh whole blood (FWB), hydroxyethyl starch 130/0.4 (HES), 4% succinylated gelatin (GELO), or 80 mL kg−1 of balanced isotonic crystalloid (CRYST).
| Group | Baseline | Shock | T60 | T180 |
|---|---|---|---|---|
| HES | 6, 0, 0, 0 | 4, 1, 1, 0 | 3, 1, 2, 0 | 4, 1, 1, 0 |
| GELO | 6, 0, 0, 0 | 4, 2, 0, 0 | 2, 3, 1, 0 | 3, 1, 2, 0 |
| FWB | 5, 0, 1, 0 | 3, 0, 2, 1 | 4, 0, 1, 1 | 4, 1, 1, 0 |
| CRYST | 6, 0, 0, 0 | 4, 1, 1, 0 | 4, 0, 2, 0 | 2, 1, 3, 0 |
| P-value* | 1.00 | 0.83 | 0.50 | 0.97 |
Fluid was delivered directly after shock time point. Data represent the number of dogs assigned to the categories of no hyperfibrinolysis, reversible hyperfibrinolysis, irreversible hyperfibrinolysis, or paradoxical increase in hyperfibrinolysis, respectively.
*
Fisher's exact test.