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Urinary excretion of Klotho normalized by creatinine excretion (A), plasma levels of Klotho (B) at the end of the experiment (8 months old) and renal protein abundance of Klotho (C) in male Zucker lean and obese rats. Data are means ± SEM. ∗p < 0.05 compared with Zucker lean rats (n = 10, each group). Means with the same letter (a or b) indicates sets of means within there are no significant difference at p < 0.05.
