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. 2018 Nov 13;9:1295. doi: 10.3389/fphar.2018.01295

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Copyright © 2018 Zhu, Wang, He, Meng and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cancer-related peptides/proteins encoded by ncRNAs. (A) Cancer-related peptides encoded by lncRNA. HOXB-AS3 is encoded by the lncRNA HOXB-AS3. HOXB-AS3 regulates tumor energy metabolism by antagonizing hnRNP A1, mediating PKM splicing. SPAR is encoded by LINC00961. SPAR interacts with the lysosomal v-ATPase to negatively regulate mTORC1 activation. (B) Cancer-related proteins encoded by circRNA. FBXW7-185aa is encoded by circ-FBXW7. FBXW7-185aa regulates the stability of the c-Myc oncoprotein. SHPRH-146aa is encoded by circ-SHPRH. SHPRH-146aa mediates the ubiquitination and degradation of PCNA. (C) Cancer-related proteins encoded by pri-miRNA. miPEP-200a and miPEP-200b are encoded by pri-miRNA (miR-200a and miR-200b). miPEP-200a and miPEP-200b affect the epithelial to mesenchymal transition of prostate cancer cells.