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. 2018 Nov 13;9:1288. doi: 10.3389/fphar.2018.01288

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Copyright © 2018 Liu, Chen, Zhao, Zhao, Qian, Shi, Baruscotti and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of active compounds by coefficient ranking. (A) Heatmap for relative content of identified compounds in each WXKL fractions. (B) Bio-active map was converted from content map and corresponding bioactivity coefficient in each fraction, and active indexes of identified compounds were calculated and showed on the right. (C) Compounds were plot by cell protection and bio-active scores and mass spectrum of several compounds on top. X axis means the contribution of compounds to the cardiomyocytes protection. Y axis means the AI of compounds.