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Evaluation of granzyme B levels for subjects included in the prospective study. (A) Grz B levels measured in culture supernatants of PBMCs from individuals, categorized basing on their home focus and their age. Horizontal bars represent median values. (B) Percentage of subjects showing high levels of GrzB (≥2,000 pg/mL; Grz B+) and those with levels <2,000 pg/mL (Grz B−). OEF: old endemic focus; NEF, New endemic focus.
