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. 2018 Nov 7;12:396. doi: 10.3389/fncel.2018.00396

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Copyright © 2018 Chen, Wu, Gu, Zhou, Ye, Zhang, Pan, Wang, Wei, Zhu, Naman, Mak, Carlier, Cui and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A10E significantly increased the expression of pERK and pAkt in the hippocampal regions of surgery-treated mice. (A) The expression of pAkt, Akt, pERK, extracellular regulated kinase (ERK) and β-actin in the hippocampal regions of mice was detected by Western blotting. Quantitative results demonstrated that treatment with A10E at 0.6 mg/kg significantly increased the expressions of (B) pAkt and (C) pERK in surgery-treated mice (n = 4). ^#p < 0.05 vs. control group and *p < 0.05 vs. the surgery group (Dunn’s multiple comparison test).